This contribution deals with problems of brownfield regeneration in the Moravian-Silesian Region. The county belongs to one from the most affected regions with the existence of brownfields in the Czech Republic. Although lately there are a lot of programs and options to their regeneration, the problem can't be solved effectively. It is clear that the occurrence of brownfields in a certain direction can influence the development of the city or municipality, last but not least, there may be pathological phenomena which may endanger the health of the population who live near brownfields. The article deals with problems of the brownfield regeneration in the given area, especially factors that in some way can influence the reuse of these objects and areas. Part of the article are secondary data within the existence of abandoned objects and areas on the given territory. This is primarily about brownfields database of the Agency CzechInvest and the company Invest MORE. Both companies are actively involved into the issue of regeneration abandoned objects and areas. Their main objective is to find a potential investor or developer who would be interested about a given brownfield. The article also deals with a primary research which is focused on the perception an existence of brownfields from the point of view of the public sector in the given territory. It is obvious that this issue from the perspective of the public sector is a very current topic that is needed nowadays to deal. More developed regions have greater a potential of an economic growth than the less developed regions. The article lists the preliminary results of the research because the research has not been completed to the date of the contribution processing.