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The aim of this article is to evaluate the business activity of small and medium enterprises in the Statutory City of Karviná in the Czech Republic. With regard to the objective of the work, a questionnaire survey focused on small and medium-sized enterprises in Karvina was carried out. Secondary data are obtained from the Czech Statistical Office. Within Karvina, the number of registered entities is approximately half the number of registered entities every year, except for cooperatives. Enterprises of natural persons doing business under the Trade Licensing Act have a considerable advantage over legal entities. The main motivating factors for entrepreneurship are the influence of “self-fulfillment” when entrepreneurs engage in entrepreneurial activity to achieve their inner satisfaction. The second main motive is the possibility to organize your time and take responsibility for yourself. From the perspective of barriers to starting a business, the most important factor is the bureaucracy and redundant administration.