The overall impact of COVID-19 on tourism enterprises and thus on other related sectors is negative, but it also has its positives in connection with sustainable tourism. The aim of the paper is to map the impact of coronavirus on the economic and social sustainability of tourism enterprises in the Czech Republic, primarily on the operators of enterprises providing accommodation and catering services, and then on their employees. In particular, secondary data obtained from publicly available sources and a comparative analysis were used, which showed that the impacts on tourism are so significant that if the situation should approach the state before the pandemic, it will take at least two to three years. It is also important to note that the behavior of clients, manufacturers and service providers is changing significantly.