Summary: By evaluating the overall condition of the patient we obtain information on the success of treatment and the impact of therapeutic interventions on patient's health. Objective: To determine the overall condition and performance of patients enrolled in the hemodialysis program. File and methods: The research group consisted of 102 respondents who were included in the dialysis program. We used the Karnofsky score (KS). Results: The average assessment of the overall condition was 63.8% for women and 64.3% for men. We proved a statistically significant relationship between Karnofsky score values and the age of the respondents and also between Karnofsky score and respondents' social status. Higher values of self-sufficiency and statistical dependence were demonstrated among the values in employed patients (80-90% KS) compared to retired patients (from 70-40% KS; p = 0.001378) and disabled pensioners (45-80 % KS; p=0,004014). Conclusion: On average, dialysis patients rate their performance as "limited." They are able to secure most of their needs themselves, only occasionally they need someone else's help. Employed respondents evaluate their performance better than disabled or old-age pensioners. With increasing age, the performance of patients decreases and their dependence on help increases, which is a natural phenomenon regardless of the presence of the diagnosis.