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The aim of the article is to make a comparison of brownfields in the South Moravian, Olomouc, Zlín and Moravian-Silesian regions based on the spatial standpoint. Data on brownfields were obtained through the National Database of Brownfields, which is managed by the CzechInvest agency. Information about these abandoned buildings and grounds were dated on 31st March 2021. The finding of the contribution is the fact that the most abandoned buildings and areas are mainly in Moravian-Silesian and South Moravian Region. Most of brownfields are after industrial activities, civic amenities and agricultural activities. In the given article, the analysis of brownfields according to individual indicators was performed on the basis of spatial and geographical point of view. It was found that most of the examined abandoned buildings and areas are located mainly in cities, which were followed by municipalities. Furthermore, it was proved that the size of brownfields from 54% is in area up to 1 (ha). The following indicator was the distance of abandoned buildings and areas from the centre of the cadastral area. Based on the results, it was found that 45% of the analysed brownfields are located 1-3 km from the centre of the cadastral area.