Czech-Polish trade relations have long been the subject of economic interest of many economic entities, due to the historical interdependence and territorial proximity of the two countries. Although the Cov-19 pandemic is still not over, it is evident that the effects caused by Cov-19 have also been reflected in the trade exchange of these two neighboring economies. The basic motive of the presented publication is to capture and contextualize the primary and secondary impacts of Cov-19 on mutual Czech-Polish foreign trade. The authors of the publication drew attention to the key theoretical starting points of the assessed issue and tried to place it in a practical context using contemporary statistical data, which are subjected to a detailed analysis within the publication. The result is a comprehensive publication that is intended to help the reader understand the complex process of selected areas of foreign trade and thus creates ideal conditions for a deeper knowledge and understanding of a number of contexts that would otherwise probably escape the reader's attention. At the same time, the purpose of the publication is not to explain the economic and political measures that were applied following the development of the pandemic.