The paper aims to analyze the theoretical framework of the middle-income trap concept, depending on the possibilities of eliminating this phenomenon, in the regional context of the Moravian-Silesian Region. The presumption of this issue works with the aim that the issue of the middle income is one of the main features that are currently appearing in modern economies to a greater or lesser extent, all the more urgently in connection with the permanent situation of coronavirus pandemics, which includes all aspects of social life in modern democratic societies within the European Union. The paper addresses the most important issues and analyses the possibilities to reduce the negative effects of the middle-income trap in longer-term periods. The text points out the position of the Moravian-Silesian Region in the Czech Republic, in terms of its powers and evaluates the possibilities that the actors of the Moravian-Silesian Region have.