We construct a large family of positive definite kernels K : Dn x Dn-+ M(r, C), holomorphic in the first variable and anti-holomorphic in the second, that are quasi-invariant with respect to the subgroup Mob x center dot center dot center dot x Mob (n times) of the bi-holomorphic automorphism group of Dn. The adjoint of the n-tuple of the multiplication operators by the co-ordinate functions is then homogeneous with respect to this subgroup on the Hilbert space ?-lK determined by K. We show that these n-tuples are irreducible, are in the Cowen-Douglas class Br(Dn) and are mutually pairwise unitarily inequivalent.