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BACKGROUND: Adolescents are at high risk of sexual health disruption, sexually transmitted infections (STIs), unplanned pregnancies and sexual violence, primarily due to cognitive and biological vulnerabilities. The best prevention strategy is to educate young people. There is substantial evidence of the effectiveness of youth and adolescent sex education programmes. Targeted sexuality education and awareness leads young people not only to delay sexual debut, reduce the frequency of sex, eliminate the number of partners, positively influence behaviours related to the prevention of unintended pregnancy and the use of condoms as one of the options for basic protection against infection, but also to understand intimacy, selfworth, sexual diversity. It is necessary to set clear and comprehensive guidelines for training and education and to implement these in practice not only in schools but also in other educational institutions for adolescents. Aim: To examine existing adolescent sexuality education programs and identify interventions and key components of comprehensive education that increase effectiveness in promoting reduction of risky sexual behavior among adolescents.