The study presents a confirmation of six quadruples with two sets of eclipses that have the 2+2 architecture. These so-called doubly eclipsing systems still present a quite rare group of stars. We collected all available photometric data and carried out a detailed analysis of them. In addition to the precise TESS photometry used to model the light curves for both inner eclipsing binaries, photometric survey data were also used, and more than 100 nights of our own dedicated observations were carried out. These were mainly used for the detection of the long-term evolution of orbital periods. Thanks to these data, we were able to derive the mutual orbits of the inner doubles via eclipse timing variations. The systems studied are: CzeV1254 (periods 0.715348 d + 0.362593 d, mutual period 15.6 yr); ASASSN-V J070838.27-171952.9 (4.300490 d + 3.767235 d, 4 yr); ASASSN-V J091951.17-593306.9 (2.668674 d + 14.342218 d, 0.95 yr); WISE J100820.07-731554.0 (0.368315 d + 7.945339 d, 3.8 yr); ASASSN-V J143536.01-721459.4 (7.353842 d + 6.368567 d, 27.4 yr); and Corot 310284765 (1.875418 d + 2.371126 d, 22.6 yr). Some of the binaries show significantly eccentric orbits. We also estimated their apsidal motion periods. With our six new systems, the number of confirmed orbits of 2+2 quadruples has been increased to 64 in total.