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Globalization is a phenomenon influencing the field of tourism, offer end demand in this field. Globalization represents one of twelve megatrends which effect tourism market elements. The article deals with development of trends in the international travel characterized according to individual authors. It mentions twelve megatrends: Mutual conditioning of globalization and localization, strengthening polarization of preferences by tourist oriented on comfort and adventure, downsizing the world for travel, informational and communicational technology, the so called fast track travel, increasing predominance of buyers, destination as a fashion accessory, creating product and marketing. This is followed by the analysis of impact of globalization on demand trends in international travel. The demand is made by customers who extremely emphasize quality, original experiences, non-traditional experiences, high comfort, and safety. Interest in cultural and sports activities, wellness or health improvement stays is sharply increasing too. Globalization influences regions therefore the article also focuses on the trends connected to globalization in The Moravian-Silesian Region (MSR). Current trends in tourism for this region are stated in The Strategy of Directing Tourism in the MSR, in the complete version of 2015. The research from 2017-2018 was targeted on services of travel agencies. The research showed that three fifths of customers use the Internet whereas one fifth uses the sale portals. Most customers focused on active and adventurous trips; the younger ones searched for extreme experience, discovered unique places; travellers very often looked for gastronomically oriented tourism.