Leaving the UK from the EU is viewed primarily as a change in the political and economic balance of power in the EU. Practically, there are ignoring the changes related to the availability and distribution channels, these changes are not so significant, particularly because of geo-spatial dislocation of Great Britain as a relatively confined island. There was simulated availability of EU regions at NUTS 2 and NUTS3 levels in this research. The paper deals with comparing of relationships before and after Brexit. The model that was used defines the distribution relationships based on the spatial distribution of NUTS regions by calculating the minimum ortodrom and reduced deviatilit. The results are useful as a basis for corporate distribution processes but also can be used for the analysis of migration, tourism and other activities related to the spatial distribution of NUTS entities and accessibility.