UONP014 Clinical Biocheistry, Clinical Hematology

Faculty of Public Policies in Opava
Winter 2021
Extent and Intensity
0/30/0. 2 credit(s). Type of Completion: z (credit).
Teacher(s)
MUDr. Jana Bjalková (lecturer)
Mgr. Simona Kudlíková (seminar tutor)
Mgr. Lenka Stanovská (seminar tutor)
Guaranteed by
MUDr. Jana Bjalková
Institute of Paramedical Health Studies – Faculty of Public Policies in Opava
Contact Person: Mgr. Veronika Slováček Hagenová
Timetable
Mon 25. 10. 15:35–18:00 C311, Mon 1. 11. 15:35–18:00 C311
  • Timetable of Seminar Groups:
UONP014/A: Wed 10. 11. 13:55–17:10 C308, Thu 18. 11. 8:55–12:10 SN01, Wed 24. 11. 10:35–13:50 C310, Wed 1. 12. 13:55–18:00 C310, Thu 9. 12. 8:55–14:40 C304, S. Kudlíková, L. Stanovská
Prerequisites (in Czech)
FAKULTA(FVP) && TYP_STUDIA(B) && FORMA(P)
Course Enrolment Limitations
The course is only offered to the students of the study fields the course is directly associated with.
fields of study / plans the course is directly associated with
Course objectives
CLINICAL BIOCHEMISTRY
The course is conceived as a theoretical-practical one. It introduces to the basic knowledge of clinical biochemistryand hematology. It innforms on the biochemical balance of the internal environment of the organism and its changes in connection to different types of diseases and disorders. The aim is to understand the diagnostic value of biochemical examination and learn basic terminology. An important part of the instruction is information on the methods and techniques for sampling of biological material, its labelling, storing and sending for processing. The course gives information on basic and special examination methods in hematology and explains the basic principles of transfusion, including the manufacture of blood products. The course describes briefly the basic parameters of laboratory determinations and also the basis of clinical practice with the aim of understanding basic metabolic relationships between the two sectors and the proper interpretation of laboratory results.
CLINICAL HEMATOLOGY
The course introduces students to the basic knowledge of clinical hematology and clinical transfusion on which other nursing courses in the field build. The course provides information on basic and special examination methods in hematology, introduces to the way of collecting blood for hematology examination, to clinical significance of individual examinations and to the way of interpreting the results. It provides an overview of the clinical practice of most frequent pathophysiological units. It introduces to the basic principles of transfusion medicine, to the organization of blood donations and blood components, laboratory methods used in transfusion medicine, the production of transfusion preparations and indications for their application, as well as post-transfusion complications. It highlights the importance of blood donation and blood-forming cells and familiarizes with their conditions. It provides information about the possibilities of hemapheretic donations.
Learning outcomes
Professional Knowledge: Students are familiarized with the basic biochemical processes occurring within the human body and is able to reproduce these findings.
Professional Skills: Students can use a correctly chosen method of sampling techniques of biological material, to the extent that it is also possible to perform basic analysis of the extracted material.
General Qualification: Students are able to explain and choose the correct method of sampling techniques for the individual patient in accordance with the clinician’s requirements.
Competences: Students are able to provide clients and their relatives information regarding this field in an appropriate form in terms of their competencies.

Professional Knowledge: Students acquire and demonstrate knowledge of basic hematology and transfusion.
Professional Skills: Students are well versed in the normal course of haematological of transfusions and identifying possible complications and responding to them according to their competencies.
General Qualification: Students are able to assist in procedures associated with the field and act within the scope of their authorisation.
Competences: Within legal boundaries, students cooperate in the administration of blood products with the physician in a way that is safe for the patient and healthcare team members.
Syllabus
  • 1. Preanalytical influences on laboratory tests. Collection of biological material.
  • 2. Laboratory diagnosis of the liver and of the biliary tract. Laboratory diagnosis of the kidneys and of the urinary tract.
  • 3. GIT Laboratory diagnosis. Laboratory diagnosis of the skeletal system.
  • 4. Laboratory diagnosis of heart.
  • 5. Laboratory diagnosis of malignant neoplasms.
  • 6. Protein metabolism. Fat metabolism. Carbohydrate metabolism.
  • 7. Endocrine system.
  • 8. Metabolism of water, ions and trace elements. Introduction to acid-base balance (ABB). Vitamins.
  • 9. Laboratory diagnosis of pregnancy.
  • 10. Introduction to instrumental analysis.
  • 1. Introduction to hematology, basic physical and chemical properties of blood.
  • 2. Hematopoiesis - its structure, functions and governing principles.
  • 3. Introduction to laboratory diagnostics in hematology. Basic parametres of blood counts and their importance. Hemoglobin, structure and function.
  • 4. Anemia - characteristics, types, therapy. Leucopenia and leucocytosis - characteristic of various conditions and diseases and their therapy. Thrombocytopenia and thrombocytosis - characteristics of various conditions and diseases and their therapy.
  • 5. Oncological hematology - leukemia, lymphomas and other lymphoproliferatives and myeloproliferatives. Donation of bone marrow and hematopoietic stem cells. Bone marrow and hematopoietic stem cells transplantation.
  • 6. Physiology and pathophysiology of blood clotting. Congenital and acquired disorders of blood coagulation. Thrombophilias, thromboembolic disease. Anticoagulant therapy.
  • 7. Organization of blood transfusion services in the Czech Republic. Donation of blood and blood components. Correct transfusion practice. Good manufacturing practice in the manufacture of blood products. Significance of examination of infectious markers in blood transfusion service.
  • 8. Immunohaematology. AB0 and Rh system - their clinical significance. Pre-transfusion testing. Hemolytic disease of the newborn.
  • 9. Transfusion products - types and indications. Blood Derivatives - types and indications. Hemovigilance and transfusion reactions. Hemaphereses.
  • 10. Blood sampling for hematologic examinations, blood counts analyzers, preanalytical phase and its importance.
  • 11. Examination of the sedimentation rate of erythrocytes, hematocrit, coagulation analyzers, interpretation of results.
  • 12. Determination of the ABO blood group system and Rh. Microscopic examination of samples.
Literature
    required literature
  • ČERMÁKOVÁ, M., ŠTĚPÁNOVÁ, J. Klinická biochemie. Brno: NCO NZO, 2005. ISBN 9788070134245. info
  • RACEK, J. Klinická biochemie. Praha:Galén, 2006. ISBN 80-7262-324-9. info
  • STANOVSKÁ, L. Klinická biochemie. Distanční studijní opora. 1. vyd. [online] Opava: Slezská univerzita v Opavě, 2012. [cit. 2012]. Dostupné z: http://elearning.fvp.slu.cz/course/
  • ŠTERN, P. a kol. Obecná a klinická biochemie. Praha: Karolinum, 2011. ISBN 978-80-246-1025-2. info
  • GALUSZKOVÁ, D. Hematologie pro sestry. Distanční studijní opora. 1. vyd. [online] Opava: Slezská univerzita v Opavě, 2012. [cit. 2012]. Dostupné z: http://elearning.fvp.slu.cz/course/
  • KUBISZ, P. a kol. Hematológia a transfuziológia. Praha: Grada Publishing, 2006. ISBN 80-247-1779. info
  • PENKA, M., TESAŘOVÁ, E. a kol. Hematologie a transfuzní lékařství. Praha: Grada Publishing, 2011. ISBN 978-80-247-3459-0. info
  • PENKA, M., TESAŘOVÁ, E. a kol. Hematologie a transfuzní lékařství II. Praha: Grada Publishing, 2012. ISBN 978-80-247-3460-6. info
    recommended literature
  • ADAM Z., KREJČI M., VORLÍČEK J. a kolektiv. Hematologie - přehled maligních hematologických nemocí. Praha: Grada Publishing, 2008. ISBN 978-80-247-2502-4. info
  • PECKA, M. a kol. Praktická hematologie - Laboratorní metody. Český Těšín: Infiniti art, 2010. ISBN 978-80903871-9-5. info
Assessment methods
Credit is awarded under the condition of fulfilment of 80% instruction attendance (students who could not attend compulsory instruction for serious reasons will be assigned an alternative way of fulfilling their study requirements) and completion of a written test.
Language of instruction
Czech
Further Comments
The course can also be completed outside the examination period.
The course is also listed under the following terms Winter 2019, Accreditation summer.
  • Enrolment Statistics (recent)
  • Permalink: https://is.slu.cz/course/fvp/winter2021/UONP014